Pregnanolone

What is Pregnanolone? Pregnanolone is an endogenous neurosteroid that is formed as a metabolite of progesterone. It is being studied for its interaction with GABA-A receptors. It is investigated for its roles in stress, mood, and neurological processes in laboratory models. Researchers investigate Pregnanolone for its possible calming and anti-anxiety effects in lab models. It could also have neuroprotective properties in preclinical models. Pregnanolone is strictly for research purposes. It is not approved for human or animal use. Chemical Properties IUPAC Name (3a,5B)-3-hydroxypregnan-20-one CAS Number 128-20-1 Molecular Formula C 21 H 34 O 2 Molecular Weight 318.501 g/mol Appearance White to off-white crystalline powder Purity ≥98% Solubility Soluble in ethanol, DMSO, and PEG; limited water solubility Storage -20℃ How does Pregnanolone work? Preclinical studies suggest Pregnanolone may act through the following mechanisms: It may act as a positive allosteric modulator of the GABA-A receptor in laboratory models. It could influence the central nervous system by promoting inhibitory neurotransmission. Pregnanolone may interact with neuroendocrine pathways. It may affect mood, sleep, and cognitive function in research models. These mechanisms are currently under investigation in laboratory research. What are the potential research benefits of Pregnanolone? In experimental models, researchers have studied the following effects of Pregnanolone. Pregnanolone has been studied for potential anti-anxiety and calming effects in animal models. Pregnanolone has been investigated for neuroprotective effects in stress-related preclinical studies. Pregnanolone may modulate seizure thresholds in neurological research. Pregnanolone has been studied for its potential to improve sleep quality in sleep disturbance models. Note: This product is intended for research purposes only. It has not been approved by the FDA for human or veterinary use. Research on Pregnanolone Studies in rodent models suggest Pregnanolone may exert sedative and anxiolytic effects without the dependence risks seen in some other GABAergic agents. In vitro studies also suggest that Pregnanolone may have neuroprotective effects under oxidative stress conditions. However, further research is needed to understand its full pharmacological profile. Where can Pregnanolone be purchased for research use? PureRawz is a trustworthy supplier if you are looking to buy Pregnanolone for research. Each purchase includes a reference-grade Certificate of Analysis . This document verifies the compound’s identity, purity, and concentration to support research compliance. Note: In the Nootropics Powder category, PureRawz offers lab-tested formulations including Picamilon Sodium, Bemethyl (Bemetil) and many other product. Is Pregnanolone legal? Pregnanolone is legal for research in some regions. Researchers must follow local and institutional regulations for legal compliance. FAQs Is Pregnanolone safe for human use? No. Pregnanolone is not approved for human or animal use. It is strictly for laboratory research. What are the side effects of Pregnanolone? Side effects have not been fully studied. Ongoing research in animal models aims to explore safety and tolerability. What is the shelf life of Pregnanolone? When stored properly at -20℃, Pregnanolone has a shelf life of up to 2 years. How should Pregnanolone be stored? Keep the compound in a cool, dry environment away from direct light. Use airtight containers to preserve stability. Disclaimer This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions . If you are not 100% satisfied with the product you received, please contact us at support@purerawz.co   ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY. It is not intended for veterinary or human use.