Phenibut HCL

  Phenibut HCl & Research Chemical Overview What is Phenibut HCl? Phenibut HCl is a synthetic analog of gamma-aminobutyric acid (GABA), a neurotransmitter involved in inhibitory signaling in the central nervous system. The compound was originally synthesized in the Soviet Union and has since been examined in experimental settings to study GABAergic signaling, behavioral responses to stress, and neurochemical regulation. Phenibut HCl is intended strictly for laboratory research use and is not approved for human or veterinary applications by the Food and Drug Administration . Chemical Properties Formal Name (aminomethyl)-benzenepropanoic acid, monohydrochloride CAS No 3060-41-1 Synonym Fenibut, PhGABA, Phenyl-GABA HCl Molecular Formula C 10 H 13 NO2. HCl Molecular Weight 215.7 g/mol Appearance Crystalline solid Purity 95% Storage Store desiccated at −20 °C for long-term stability Mechanism of Action (Research Context) Phenibut HCl is structurally modified with a phenyl ring, which is believed to enhance central nervous system penetration compared with GABA. In experimental systems, Phenibut primarily acts as a GABA_B receptor agonist. Laboratory studies also explore whether it interacts with dopaminergic signaling pathways and inhibitory neural circuits. Because of these properties, Phenibut is often used in research investigating: inhibitory neurotransmission behavioral stress responses sleep–wake regulatory mechanisms neural excitation control Research Areas Investigated for Phenibut HCl Phenibut HCl has been examined in various experimental models, including: Behavioral Stress Models Rodent studies frequently examine how GABA_B receptor activation influences stress-related behavioral markers and neural inhibition. Cognitive Performance Under Stress Some laboratory work evaluates how inhibitory neurotransmission affects attention, memory, and emotional processing in controlled experimental conditions. Sleep–Wake Regulation Researchers use Phenibut in experimental paradigms exploring neural mechanisms involved in sleep initiation, sedation pathways, and excitatory–inhibitory balance. Experimental Ischemia and Neurochemical Models In vitro and animal models sometimes investigate how modulation of inhibitory signaling influences neuronal responses under metabolic or oxygen-deprivation conditions. Purchasing Phenibut HCl for Research Researchers seeking Phenibut HCl should obtain materials from suppliers that provide analytical verification and batch documentation. PureRawz supplies research-grade materials accompanied by Certificates of Analysis describing identity, purity, and concentration. Regulatory status varies by jurisdiction, and researchers should verify local regulations before ordering or using any research chemical. Frequently Asked Questions Is Phenibut HCl approved for human use? No. Phenibut HCl is not approved for human or veterinary use and is intended solely for laboratory research. Are safety data available? Published literature describes pharmacological and tolerance-related observations in experimental and clinical contexts, but comprehensive safety profiles remain limited. What is the shelf life of Phenibut HCl? Stability depends on packaging, humidity exposure, and storage conditions. When stored desiccated at −20 °C, research materials typically retain stability for extended periods. How should Phenibut HCl be stored? Store tightly sealed in a dry environment at −20 °C. Avoid repeated freeze-thaw cycles and moisture exposure. Disclaimer This material is provided for educational and research information purposes only. Products are intended strictly for laboratory research use. Where applicable, studies should comply with institutional biosafety, ethical, or regulatory review requirements. Researchers are responsible for verifying compliance with local regulations before use or purchase. ATTENTION: All products are supplied for laboratory research purposes only and are not intended for human or veterinary applications.