ACTH 1-39 Peptide For Sale At Best Prices.
What is ACTH 1-39?
ACTH 1-39, formally known as adrenocorticotropic hormone 1-39, is a peptide hormone that plays a significant role in regulating adrenal gland function and hormone production, particularly cortisol. Derived from the broader adrenocorticotropic hormone family, this specific fragment retains the core functional components of the parent hormone while offering researchers a more targeted compound for scientific study.
Through extensive laboratory investigation, researchers have identified ACTH139 as a catalyst for cortisol production, muscle cell activity, metabolic regulation, and modulation of the hypothalamic-pituitary-adrenal (HPA) stress axis, making it a compound of considerable scientific interest.
ACTH139 Product Details
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Property |
Details |
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CAS Number |
12279-41-3 |
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Molar Mass |
4541 g/mol |
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Chemical Formula |
C207H308N56O58S |
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Also Known As |
Adrenocorticotropic Hormone 1-39 |
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Research Use |
Laboratory and Scientific Research Only |
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Available Forms |
Liquid, Powder, Capsule |
Understanding the HPA Stress Axis
The hypothalamic-pituitary-adrenal (HPA) stress axis is a neuroendocrine system that governs the body’s response to stress. This system involves three key components: the hypothalamus, the pituitary gland, and the adrenal glands. When the body encounters stress, this axis triggers the release of hormones including corticotropin-releasing hormone (CRH) and ACTH, which in turn stimulate cortisol production. Cortisol plays a central role in regulating the immune system, metabolism, and overall stress response. Disruption of the HPA axis has been linked to a range of health conditions, making a thorough understanding of this system valuable for researchers studying stress-related disorders.
How Does ACTH1-39 Work?
The precise mechanism of action of ACTH 1-39 is still under active scientific investigation. However, current research has shed light on several pathways through which this compound may exert its effects.
ACTH1-39 is believed to bind to specific receptors found across various cell types throughout the body. This receptor binding is thought to trigger downstream signaling pathways responsible for its wide range of biological effects. Specifically, ACTH 1-39 acts as an agonist on endogenous melanocortin receptors, which are present in multiple cell types including muscle cells and cells within the central nervous system. Upon binding to these receptors, this peptide initiates a series of cellular responses that may lead to the release of corticosteroids and androgenic steroids.
From a neurological standpoint, ACTH139 may also influence neurotransmitter activity in the brain. By affecting the release, reuptake, or receptor interactions of key chemical messengers, it could have an impact on neuronal function and plasticity. Researchers have also noted its potential involvement in metabolic syndrome and its modulatory role within the HPA stress axis. (R)
ACTH139 Research Applications
ACTH 1-39 and Neurological Research
A study published in the Journal of Neuroscience examined the effects of ACTH 1-39 on neuronal adaptability. Findings indicated that ACTH 1-39 supported enhanced synaptic plasticity and improved neuronal resilience. These results suggest potential applications in cognitive research and the study of neurological health and protection.
ACTH 1-39 and Immune System Research
Research published in the Journal of Immunology investigated the ability of ACTH 1-39 to influence immune responses. The study found that ACTH139 notably reduced inflammation-related damage and helped regulate immune cell activation. These findings highlight its potential value in the study of immunological conditions, including autoimmune disorders.
ACTH 1-39 and Metabolic Regulation Research
A comprehensive study featured in the journal Diabetes explored the impact of ACTH 1-39 on glucose balance and insulin sensitivity. Researchers found that ACTH139 contributed to improved glucose tolerance, enhanced insulin sensitivity, and better pancreatic beta cell function. These outcomes suggest that ACTH139 could be a valuable compound in research targeting metabolic conditions such as type 2 diabetes.
ACTH 1-39 and Anti-Inflammatory Research
An animal study published in the Journal of Inflammation assessed the anti-inflammatory potential of ACTH 1-39. Results showed a significant reduction in pro-inflammatory cytokine production and decreased tissue damage in an experimental inflammation model. These findings position ACTH139 as a promising compound for researchers focused on developing anti-inflammatory strategies.
Research Applications at a Glance
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Research Area |
Key Finding |
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Neurological Research |
Improved synaptic plasticity and neuronal resilience |
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Immune System Research |
Reduced inflammation and regulated immune cell activation |
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Metabolic Research |
Enhanced glucose tolerance and insulin sensitivity |
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Anti-Inflammatory Research |
Decreased pro-inflammatory cytokine production |
Frequently Asked Questions
How is ACTH 1-39 studied?
ACTH 1-39 is examined through both in vitro studies, which involve cell-based experiments, and in vivo studies conducted on animal models. These approaches help researchers better understand how the compound interacts within biological systems and what effects it may produce.
What are the potential implications of ACTH139 research?
Findings from ACTH139 research may contribute to the development of new therapeutic approaches targeting neurological, immunological, and metabolic conditions. While research is still ongoing, the early findings are promising across multiple scientific disciplines.
Where to Buy ACTH 1-39 Online
Purerawzus.com is your trusted source to buy high-purity ACTH 1-39 for scientific research. Every product we carry is rigorously tested and backed by full documentation so you can order with complete confidence.
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Feature |
Details |
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Purity |
99%+ verified purity |
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Testing |
Independent third-party lab tested |
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Documentation |
Certificate of Analysis (COA) included |
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Available Forms |
Liquid, Powder, Capsule |
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Shipping |
Free international shipping on orders over $100 |
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Payment Options |
Multiple secure payment methods available |
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Support |
24/7 expert customer support |
Disclaimer
All content provided on this page is strictly for educational and informational purposes and does not constitute medical advice. All products available on Pure rawz USA are intended for laboratory and research use only. Clinical research must be conducted under the supervision of an appropriate Institutional Review Board (IRB). Preclinical research must adhere to the guidelines of the Animal Welfare Act (AWA) under the oversight of the relevant Institutional Animal Care and Use Committee (IACUC). We strongly encourage all customers to conduct independent research from trusted sources before completing any purchase. By placing and paying for your order, you agree to our Terms and Conditions. If you are not fully satisfied with your purchase, please contact us at sales@purerawzus.com and we will resolve the issue promptly.
All products sold on Purerawzus.com are for laboratory and research purposes only and are not intended for veterinary or human use.






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