Alarelin Acetate Alarelin acetate is a synthetic gonadotropin-releasing hormone (GnRH) agonist peptide. The peptide’s structure is derived from endogenous GnRH, with specific amino-acid modifications. The modifications help increase its resistance to enzymatic degradation in experimental models. Alarelin acetate is being researched by various analysts in reproductive endocrinology studies. The researchers also investigate the peptide in hypothalamic–pituitary–gonadal (HPG) axis regulation studies. Moreover, the researchers explore Alarelin Acetate in different research settings for its potential influence on hormone-dependent reproductive processes and peptide–receptor interactions. Alarelin acetate is classified as a research compound and is not approved for clinical or therapeutic use in humans. Chemical Properties Pubchem CID 12821051 Molecular Formula C 60 H 86 N 16 O 16 Synonyms ALARELIN ACETATE 288L2XKV2J LHRHa RefChem:1076311 Leutenizing Hormone-Releasing Hormone analogue Molecular Weight 1287.4 g/mol IUPAC L-pyroglutamyl-L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-alanyl-L-leucyl-L-arginyl-L-proline ethylamide acetic acid Solubility DMF: 5 mg/ml DMSO: 5 mg/ml PBS (pH 7.2): 5 mg/ml CAS 79561-22-1 How Does Alarelin Acetate Work? Alarelin acetate appears to work in experimental models by interacting with GnRH receptors in the pituitary gonadotroph cells. The interaction influences the release of primary reproductive hormones: luteinizing hormone (LH) and follicle-stimulating hormone FSH). Researchers believe that with constant stimulation, the GnRH receptors become less responsive and their number decreases. This ultimately reduces pituitary responsiveness, resulting in a decline in the secretion of LH and FSH declines in experimental models. This decline further results in suppressed spermatogenesis in males and impaired follicular development and ovulation in female research models. Storage and Handling Guidelines Handling and storing of Alarelin Acetate peptide is important for long-term research use. Here are the guidelines to follow: Always store the Lyophilized (powder) form of Alarelin Acetate in –20°C to –80°C The reconstituted solution can be refrigerated at 2–8°C (refrigerated) Use sterile bacteriostatic water or sterile saline Allow the vial to reach room temperature before opening Use sterile gloves and syringes Keep vials closed when not in use Avoid exposure to air, light, and humidity Research Application of Alarelin Acetate Alarelin Acetate is being researched by various medical analysts in laboratory settings for its following potential applications. Reproductive Endocrinology Research The peptide is being studied to understand regulation of the hypothalamic–pituitary–gonadal (HPG) axis in research models. Fertility and Ovulation Research Studies Alarelin Acetate is used in research models to investigate ovulation induction and follicular development. Moreover, researchers explore the peptide for its reproductive hormone dynamics. Hormone-Dependent Disorder Research A few medical researchers explore the peptide’s efficacy related to endometriosis and uterine fibroids. Furthermore, the peptide is also being investigated for other estrogen-dependent conditions in research models. Buy Alarelin Acetate Online If you are looking to buy Alarelin Acetate, then Purerawz should be on your list. We provide you with premium quality Alarelin Acetate at unbeatable prices. You can order first and third-party tested Alarelin Acetate for your research purposes. We provide you with a proper Certificate of Analysis as well, so that you have little to no doubt about our products. Disclaimer This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions . If you are not 100% satisfied with the product you received, please contact us at support@purerawz.co ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human use Reference Links Yuan, F., Zhang, P., Liu, M., Li, Y., Xu, B., & Li, X. (2025). Pharmacogenomic analysis of alarelin acetate-induced hepatotoxicity: a case report and literature review. Frontiers in Medicine, 12. https://doi.org/10.3389/fmed.2025.1634101 Yuan, F., Zhang, P., Liu, M., Li, Y., Xu, B., & Li, X. (2025). Pharmacogenomic analysis of alarelin acetate-induced hepatotoxicity: a case report and literature review. Frontiers in Medicine, 12. https://doi.org/10.3389/fmed.2025.1634101
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