GW 0742 for Sale | 3rd-Party Tested Pure | Purerawz PPARβ/δ Agonist Research Compound
What is GW 0742?
Within the expanding field of metabolic research, PPARβ/δ agonists have emerged as one of the most scientifically compelling compound classes for studying fat oxidation, insulin sensitivity, and glucose homeostasis in experimental models. GW 0742 represents the most advanced research tool in this category.
GW 0742 is a potent synthetic PPARβ/δ (Peroxisome Proliferator-Activated Receptor beta/delta) agonist that has attracted significant scientific attention for its possible role in metabolic regulation, inflammation control, and cardiovascular function in preclinical research models. Often referenced in scientific literature as a structurally advanced analog of Cardarine (GW501516), GW 0742 shares the same receptor target family while offering a distinct fluorinated molecular profile that differentiates its research characteristics. Originally developed by GlaxoSmithKline, GW 0742 has since become a widely studied research compound across metabolism, diabetes, hypertension, and inflammatory biology research disciplines. All products on Purerawzus.com are strictly intended for laboratory and research use only and are not approved by the FDA for human or veterinary use.
GW 0742 Chemical Properties
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Property |
Details |
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CAS Number |
317318-84-6 |
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Molar Mass |
471.48 g/mol |
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Chemical Formula |
C21H17F4NO3S2 |
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IUPAC Name |
2-[4-[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl]methylsulfanyl]-2-methylphenoxy]acetic acid |
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Classification |
PPARβ/δ Receptor Agonist |
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Developer |
Originally developed by GlaxoSmithKline |
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Research Use |
Laboratory and Scientific Research Only |
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Regulatory Status |
Not approved by the FDA for human or veterinary use |
How Does GW 0742 Work?
Scientific investigation has identified several interconnected mechanisms through which GW 0742 may exert its metabolic and biological effects in preclinical research models:
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Potential Mechanism |
Research Context |
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PPARβ/δ Receptor Activation |
Primarily activates PPARβ/δ nuclear receptors involved in metabolic regulation |
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Fatty Acid Oxidation Stimulation |
May stimulate the utilization of fat as fuel increasing oxidative metabolism |
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AMPK Activity Enhancement |
Studies suggest possible increases in AMPK activity linked to metabolic regulation |
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Androgen Receptor Antagonism |
Demonstrates weak antagonism of androgen receptors in research settings |
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Vitamin D Receptor Interaction |
Has shown interaction with vitamin D receptors in preclinical research models |
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Thyroid Hormone Receptor Effects |
Has demonstrated effects on thyroid hormone receptors in laboratory studies |
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Glucose Homeostasis Support |
May improve glucose uptake through PPAR-δ activation in diabetic research models |
GW 0742 vs Cardarine Research Comparison
Understanding the distinction between GW 0742 and Cardarine is essential for researchers selecting the most appropriate PPARβ/δ compound for their specific study requirements:
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Feature |
GW 0742 |
Cardarine (GW501516) |
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Receptor Target |
PPARβ/δ agonist |
PPARβ/δ agonist |
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Developer |
GlaxoSmithKline |
GlaxoSmithKline |
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Molecular Structure |
Two hydrogen and four fluorine atoms |
One hydrogen and three fluorine atoms |
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Classification |
Fluorinated Cardarine analog |
Parent PPARβ/δ compound |
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Insulin Resistance Research |
Studied in diabetic and obese research models |
Studied in metabolic research models |
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Fatty Acid Oxidation Research |
Being investigated in preclinical models |
Established research applications |
Potential Benefits of GW 0742 in Research
Animal and cell-based scientific investigation has highlighted several areas where GW 0742 may offer significant preclinical research value:
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Potential Benefit |
Research Context |
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Metabolic Research |
Studies suggest possible diet-induced weight loss and visceral fat reduction in research models |
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Insulin Sensitivity Research |
Being studied for its possible role in improving insulin sensitivity in diabetic research models |
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Fat Oxidation Research |
May stimulate fatty acid oxidation and fat utilization in metabolic research settings |
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Glucose Homeostasis Research |
Studies suggest possible improvement of glucose uptake in diabetic animal models |
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Anti-Inflammatory Research |
Being explored for its possible role in reducing inflammatory markers in research models |
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Hypertension Research |
Animal studies suggest possible blood pressure reduction in hypertensive research models |
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Muscle Oxidative Capacity Research |
May increase skeletal muscle oxidative capacity in exercise and obesity research models |
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Diabetes Research |
Being investigated as a possible PPAR-δ targeted approach in diabetes research models |
Please note: All benefits listed are based on animal and cell-based preclinical research. Human clinical research on GW 0742 remains limited. This product is strictly intended for research purposes only.
Potential Research Areas of GW 0742
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Research Area |
Potential Focus |
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Metabolic Regulation Research |
Studying PPARβ/δ activation and its effects on fat oxidation and metabolic function |
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Insulin Resistance Research |
Investigating its possible role in improving insulin sensitivity in diabetic research models |
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Obesity and Fat Loss Research |
Exploring its possible influence on visceral fat reduction and weight management mechanisms |
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Glucose Homeostasis Research |
Studying PPAR-δ mediated glucose uptake improvements in diabetic animal research |
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Anti-Inflammatory Research |
Investigating its possible role in reducing inflammatory and apoptotic markers |
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Hypertension Research |
Exploring PPARβ as a research target for blood pressure regulation in research models |
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Exercise Metabolism Research |
Studying its possible influence on immune-metabolic changes induced by exercise |
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Cardiovascular Research |
Investigating its possible cardioprotective applications in preclinical research settings |
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Diabetes Research |
Exploring PPAR-δ targeted approaches for anti-diabetic mechanism research |
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Skeletal Muscle Research |
Studying its possible effects on skeletal muscle inflammation and oxidative capacity |
GW 0742 Research Findings
Metabolism and Fat Oxidation Research
A preclinical study investigating the effects of PPARβ/δ agonist treatment on immune-metabolic changes in diet-induced obese mice demonstrated increased fatty acid oxidation gene expression and elevated AMPK activity. Associated findings included reduced visceral adipose tissue mass, decreased skeletal muscle inflammation, and improved skeletal muscle oxidative capacity and insulin sensitivity in research subjects.
Insulin Resistance Research
GW 0742 has been studied for its possible ability to address metabolic abnormalities including insulin resistance in skeletal muscle tissue in mice maintained on high-fructose corn syrup diets. While promising results have been observed in these models the broader influence of GW 0742 on systemic insulin sensitivity continues to be investigated.
Inflammation Research
A dedicated preclinical investigation into GW 0742’s effects on inflammatory pathways found that this PPARβ/δ agonist reduced several inflammatory and apoptotic parameters in research models. Studies demonstrated possible reduction of lung inflammation induced by bleomycin exposure in mouse research subjects.
Diabetes Research
Animal-based research has suggested that GW 0742 may improve glucose homeostasis in diabetic research models through PPAR-δ activation pathways. These findings have led researchers to propose PPAR-δ as a potentially valuable target for future anti-diabetic mechanism research and investigation.
Hypertension Research
A 2011 preclinical study investigated whether GW 0742 might demonstrate anti-hypertensive effects in spontaneously hypertensive rat research models. Results suggested a progressive reduction in systolic arterial blood pressure and heart rate, leading researchers to propose PPARβ as a new target of interest in hypertension mechanism research.
Where to Buy GW 0742 Online
Purerawzus.com supplies COA-verified, high-purity research compounds with fast USA shipping on every order. Every purchase is backed by an independent Certificate of Analysis confirming compound identity, purity, and concentration for complete research compliance and documentation transparency. We offer multiple secure payment options including cryptocurrency and traditional payment methods to make your ordering experience seamless. Visit our how to pay page for a complete step by step guide to all available payment methods and secure checkout instructions.
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Feature |
Details |
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Testing |
Independent third-party lab tested |
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Documentation |
Certificate of Analysis (COA) included with every order |
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Shipping |
Free international shipping on orders over $100 |
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Payment Options |
Multiple secure payment methods available |
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Support |
24/7 expert customer support |
Is GW 0742 Legal?
GW 0742 is legal to purchase and sell as a research chemical in applicable regions. This designation restricts its use strictly to scientific and research purposes only. Researchers must ensure full compliance with all applicable local laws and institutional research guidelines before purchasing or using this compound.
Frequently Asked Questions
Is GW 0742 Safe for Human Consumption?
No. The FDA has not approved GW 0742 for human or veterinary use. Purerawzus.com supplies this compound strictly for laboratory and scientific research purposes only.
Does GW 0742 Improve Glucose Metabolism in Research Models?
Animal study data has suggested that GW 0742 may improve glucose homeostasis in diabetic research models through PPAR-δ activation pathways. These findings remain under active scientific investigation and require further research to fully establish their broader implications.
How Does GW 0742 Differ From Cardarine in Research?
Both GW 0742 and Cardarine target the PPARβ/δ receptor and were originally developed by GlaxoSmithKline. The primary structural distinction is that GW 0742 contains two hydrogen and four fluorine atoms while Cardarine contains one hydrogen and three fluorine atoms, making GW 0742 a fluorinated analog of Cardarine with a distinct molecular research profile.
What Side Effects Have Been Observed With GW 0742?
As GW 0742 research remains primarily limited to animal and cell-based studies its complete side effect profile in broader research contexts has not yet been fully established. Human clinical research is currently limited. Researchers are encouraged to follow all applicable laboratory safety protocols when handling this compound.
Disclaimer
All information on this page is provided for educational purposes only and does not constitute medical or professional advice. Products are for laboratory and research use only. By ordering you agree to our Terms and Conditions. Contact us at sales@purerawzus.com for any concerns.
All products are for laboratory and research purposes only and are not intended for veterinary or human use.


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